Ibuprofen is used primarily to treat fever (including post-vaccination fever), mild to moderate pain (including pain relief after surgery), painful menstruation, osteoarthritis, dental pain, headaches, and pain from kidney stones. Motrin (ibuprofen) is used to treat mild to moderate pain. Learn side effects, dosage, drug interactions, warnings, patient labeling, reviews, and more. Overview: Ibuprofen is used to reduce fever, pain, and swelling. It works by blocking certain substances in the body that cause pain, inflammation, and fever. Common side effects include stomach. Motrin IB is a nonsteroidal anti-inflammatory drug (NSAID). Ibuprofen works by reducing hormones that cause inflammation and pain in the body. Motrin IB is used to reduce fever and treat pain or inflammation caused by many conditions such as headache, toothache, back pain, arthritis, menstrual cramps, or minor injury. Motrin (ibuprofen) is a widely used over-the-counter pain reliever and anti-inflammatory medication. Dosage varies by age, weight, and medical condition, with specific guidelines for adults and children. For relief from muscle aches, fevers, cramps, & more, MOTRIN® is pain relief you can count on. Learn how MOTRIN® can help relieve pain for you & your child. Ibuprofen (Advil, Motrin) treats minor aches and pains caused by the common cold, headaches, toothaches, back or muscle aches. Find pain relief from muscle aches, period pain, minor arthritis pain, toothaches and headaches, and reduce fever with MOTRIN® IB tablets with ibuprofen 200mg. Motrin IB is a nonsteroidal anti-inflammatory drug (NSAID) that helps temporarily target pain at the source of inflammation. A fever reducer and a fast-acting pain reliever, it takes on minor muscle aches, headaches, backaches and toothaches. Motrin IB is a nonsteroidal anti-inflammatory drug (NSAID) that helps temporarily target pain at the source of inflammation. A fever reducer and a fast-acting pain reliever, it takes on minor muscle aches, headaches, backaches and toothaches.